- How happens Uric acid in the body?
- Too much uric acid can jointsbut also ships and organs damage
- medication against gout
- Tips for dealing with adequate nutrition can reduce uric acid in the body
Uric acid is a breakdown product that our body produces every day. Uric acid concentration is measured in blood serum and should not exceed certain reference values. In addition to urea and creatinine, uric acid belongs to the so-called urinary substanceswhich must be excreted in the urine. They are therefore used as markers of kidney health. In case of high values, different causes can be considered, which can lead to inflammatory reactions, such as drop, but can also cause kidney and ureter stones. In addition to genetic causes or other diseases, choice of food one of the main causes of too much uric acid in the body. Anyone who eliminates certain foods from their diet and follows a balanced diet can do their job Permanently lowered uric acid levels.
How is uric acid formed in the body?
Uric acid is formed during the breakdown of purines. These are part of every cell and are needed for genetic material and building new cells. Above purine foods such as high-fat meat, certain types of fish, or high-sugar fruits, we take in additional purines, which the body must also metabolize. The consumption of fructose (fructose) are increasingly at the center of research concerns. Because fructose is added to many products in the food industry, for example in the form of corn starch, for example when sweetening soft drinks. But also to Breakdown of the body’s own cells accumulate purines. This is particularly the case with chemotherapy.
Also has uric acid positive effects and is important for protection against free radicals. She acts here as Antioxidant, protects against free radicals and has a protective effect on tissues. From the so-called hyperuricaemia experts say when the concentration of uric acid in the blood serum exceeds 6.7 mg/dl in women and 7.4 mg/dl in men. There are two different forms:
- Primary hyperuricaemia: It’s a genetic disorder, which can affect both uric acid formation and uric acid excretion. Some enzymes important for uric acid metabolism only work to a limited extent.
- Secondary hyperuricaemia: Come here various diseases or the effects of medication in the study. Disorders of blood formation, blood cancer (leukemia), kidney disease, alcoholism or dehydrating drugs (diuretics) can cause an increase in uric acid concentration.
Too much uric acid can damage joints, but also blood vessels and organs
Too much uric acid in the body does not always cause symptoms. However, if the uric acid concentration continued exceeds a certain limit, form uric acid crystals from which are found in the tissues of the body to pay to be able.
drop belongs to the most common inflammatory joint diseases in Germany. To acute gout attack the body tries to break down the uric acid crystals in the joint via an inflammatory reaction. The typical symptoms of inflammation then appear, such as overheating, swelling, redness and very intense pain. are common affected jointswhich are far from the center of the body and have less blood supply. Typically, acute gout attacks first appear in the metatarsophalangeal joint, followed by the knee, elbow, wrist, and finger joints. Coolness favors the precipitation of uric acid crystals, as does the low pH of tissues. So can also infections and physical exertion trigger a gout attack. Gout patients are usually male, overweight, and have high blood pressure, diabetes, or kidney dysfunction.
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Additionally, there is much to suggest that too much uric acid Cardiovascular system and vessels can damage. Long before the first gout attack, crystallizing uric acid can also development of kidney stones promote and prevent drainage.
Due to the massive inflammatory processes in the body, doctors see the need for Permanently lowered uric acid levels. According to the “S2 guideline for gouty arthritis”, in the event of an acute attack of gout, the inflammation and pain should be treated first. The drug of choice in an acute gout attack colchicine, a natural substance of the autumn crocus, a poisonous plant. Finding the dose is often difficult, however, as symptoms of poisoning can occur under certain circumstances.
After surviving a gout attack, with a long term therapy begin to prevent a chronic course. However, drug treatment is also included Side effects connected so that a detailed recognition in a doctor-patient discussion greatly increases treatment success.
Especially supposedly uricostatics used, such as allopurinol or febuxostat. These inhibit an enzyme that reduces the formation of uric acid. There are also drugs that increase uric acid excretion (uricosurics) such as probenecid or benzbromarone.
Tips on how to reduce the level of uric acid in the body with the right diet
The upper limit of 500 milligrams of purines should not be exceeded daily. In acute gout attacks, a limit of 300 milligrams is recommended. A good overview of the uric acid content is provided by food table at gichtinfo.de. To keep purine exposure low, a diet change be very effective. You should note the following tips:
1. Watch out for excess vegetarian and alkaline foods food: the said DASH Diet (Dietary Approaches to Stop Hypertension), which is based on a typical Mediterranean diet, is actually recommended for patients with high blood pressure and high cholesterol levels. However, a study was able to show that a reduction in uric acid levels is also achieved. In general, the following foods should be on your menu:
- Vegetables, sour cherries, berries
- Low-fat dairy products, especially yogurt, cottage cheese, and hard cheese
- organic eggs
- grain products or flakes
- Potatoes, egg noodles, rice
2. Avoid foods high in purines: It is important that you not too many purines at once Take yours For example, you should not combine high-fat meals with meat and alcohol. For example, it can be used as a guide only in 150 grams of meat or chicken contains about half the amount of purines you should consume daily – about 210 milligrams. But smaller portions of meat can also be prepared tasty, for example as sliced meat. at the same time it helps skin removal to save a lot of purines in fish, meat, or chicken, as well as avoiding high-fat sausages and organ meats. legumes and soy products However, contrary to previous recommendations, they are in moderation (about 2x per week) harmless.
3. Forget fructose: The fructose in fruit is generally not a problem if the whole fruit is eaten. sour cherries it is even attributed a hypouricogenic effect. But also berries are low in sugar. However, it is necessary to avoid dried fruits and agave syrup and especially finished products such as soft drinks, where Fructose as a sweetener is added. When fructose is broken down, uric acid is formed.
4. Drink enough: Two to three liters of water, unsweetened herbal and fruit teas, and coffee are recommended. This allows uric acid to be better excreted. what is critical alcohol to consider because it stimulates the formation of uric acid and at the same time inhibits excretion by the kidneys. Beer, which itself contains purines is considered the worst choice, even in the non-alcoholic version.
5. Maintain a healthy weight: This helps to protect the joints and, in combination with a healthy diet, to reduce the concentration of uric acid. However, you should radical fasting cures keep away. Indeed, so-called ketone bodies are formed, which inhibit the excretion of uric acid. Also, due to the rapid reduction in body mass, more purines are broken down and the concentration of uric acid increases.
6. Food supplements after medical consultation: A large-scale study suggests that the daily intake of 500 to 1,500 mg of vitamin C effective protection against gout. Researchers suspect that it inhibits inflammatory processes and lowers uric acid concentration. However, it is important to maintain a healthy lifestyle. You should also consult a doctor before taking high dose dietary supplements.
Persistently high uric acid levels have been shown to damage the jointsbut also the ships and internal organs. One is particularly painful gout attack, in which uric acid crystals are broken down by a strong inflammatory reaction. In order to keep uric acid so low that it can be completely excreted with urine, you should go to a vegetarian, low-fat, low-fructose diet respect, think highly. the said DASH Dietthat aims for long-term dietary change. In addition, high dose intake of vitamin C to effectively reduce uric acid after medical consultation.
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